12 June 2018

By Dr Wendy Winnall - PCFA Research Team

PARP Protein Structure

Olaparib (Lynparza) is a breast and ovarian cancer drug that is being trialled for prostate cancer patients. Previous trials have shown that men with metastatic castration resistant prostate cancer benefit from Olaparib if they have mutations in DNA repair genes. Exciting results from a newly published trial show that Olaparib works for men without these gene mutations, if the drug is combined with Abiraterone (Zytiga).

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